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Electrostatic Clustering and Free Energy Calculations Provide a Foundation for Protein Design and Optimization
Electrostatic interactions are ubiquitous in proteins and dictate stability and function. In this review, we discuss several methods for the analysis of electrostatics in protein–protein interactions. We discuss alanine-scanning mutagenesis, Poisson–Boltzmann electrostatics, free energy calculations...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Springer US
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069318/ https://ncbi.nlm.nih.gov/pubmed/21140293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-010-0226-9 |
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