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Haplotype-based profiling of subtle allelic imbalance with SNP arrays

Due to limitations of surgical dissection and tumor heterogeneity, tumor samples collected for cancer genomics studies are often heavily diluted with normal tissue or contain subpopulations of cells harboring important aberrations. Methods for profiling tumor-associated allelic imbalance in such sce...

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Bibliografiske detaljer
Main Authors: Vattathil, Selina, Scheet, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530675/
https://ncbi.nlm.nih.gov/pubmed/23028187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.141374.112
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