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Using Bacteria to Determine Protein Kinase Specificity and Predict Target Substrates

The identification of protein kinase targets remains a significant bottleneck for our understanding of signal transduction in normal and diseased cellular states. Kinases recognize their substrates in part through sequence motifs on substrate proteins, which, to date, have most effectively been eluc...

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Autors principals: Chou, Michael F., Prisic, Sladjana, Lubner, Joshua M., Church, George M., Husson, Robert N., Schwartz, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530509/
https://ncbi.nlm.nih.gov/pubmed/23300758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052747
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