Lack of Avidity Maturation of Merozoite Antigen-Specific Antibodies with Increasing Exposure to Plasmodium falciparum amongst Children and Adults Exposed to Endemic Malaria in Kenya

BACKGROUND: Although antibodies are critical for immunity to malaria, their functional attributes that determine protection remain unclear. We tested for associations between antibody avidities to Plasmodium falciparum (Pf) antigens and age, asymptomatic parasitaemia, malaria exposure index (a dista...

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Bibliographische Detailangaben
Hauptverfasser: Ibison, Frances, Olotu, Ally, Muema, Daniel M., Mwacharo, Jedida, Ohuma, Eric, Kimani, Domtila, Marsh, Kevin, Bejon, Philip, Ndungu, Francis M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530478/
https://ncbi.nlm.nih.gov/pubmed/23300828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052939
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