Lack of Avidity Maturation of Merozoite Antigen-Specific Antibodies with Increasing Exposure to Plasmodium falciparum amongst Children and Adults Exposed to Endemic Malaria in Kenya

BACKGROUND: Although antibodies are critical for immunity to malaria, their functional attributes that determine protection remain unclear. We tested for associations between antibody avidities to Plasmodium falciparum (Pf) antigens and age, asymptomatic parasitaemia, malaria exposure index (a dista...

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Detalhes bibliográficos
Main Authors: Ibison, Frances, Olotu, Ally, Muema, Daniel M., Mwacharo, Jedida, Ohuma, Eric, Kimani, Domtila, Marsh, Kevin, Bejon, Philip, Ndungu, Francis M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530478/
https://ncbi.nlm.nih.gov/pubmed/23300828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052939
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