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Angiotensin II Protects Primary Rat Hepatocytes against Bile Salt-Induced Apoptosis

Angiotensin II (AT-II) is a pro-fibrotic compound that acts via membrane-bound receptors (AT-1R/AT-2R) and thereby activates hepatic stellate cells (HSCs). AT-II receptor blockers (ARBs) are thus important candidates in the treatment of liver fibrosis. However, multiple case reports suggest that AT-...

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Bibliografske podrobnosti
Main Authors: Karimian, Golnar, Buist-Homan, Manon, Mikus, Bojana, Henning, Robert H., Faber, Klaas Nico, Moshage, Han
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530435/
https://ncbi.nlm.nih.gov/pubmed/23300732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052647
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