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High levels of IL-7 cause dysregulation of thymocyte development
IL-7 signaling is required for thymocyte development and its loss has a severe deleterious effect on thymus function. Thymocyte–stromal cell interactions and other mechanisms tightly regulate IL-7 expression. We show that disruption of that regulation by over-expression of IL-7 inhibits T-cell devel...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530313/ https://ncbi.nlm.nih.gov/pubmed/22899673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxs067 |
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