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An Overview of IL-7 Biology and Its Use in Immunotherapy
Interleukin (IL)-7 is required for T-cell development as well as for the survival and homeostasis of mature T-cells. In the thymus, double negative (DN) CD4(−) CD8(−) thymocyte progenitor transition into double positive CD4(+) CD8(+) cells requires Notch and IL-7 signaling. Importantly, IL-7 seems t...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826542/ https://ncbi.nlm.nih.gov/pubmed/20017587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/15476910903453296 |
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