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An Overview of IL-7 Biology and Its Use in Immunotherapy

Interleukin (IL)-7 is required for T-cell development as well as for the survival and homeostasis of mature T-cells. In the thymus, double negative (DN) CD4(−) CD8(−) thymocyte progenitor transition into double positive CD4(+) CD8(+) cells requires Notch and IL-7 signaling. Importantly, IL-7 seems t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: ElKassar, Nahed, Gress, Ronald E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826542/
https://ncbi.nlm.nih.gov/pubmed/20017587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/15476910903453296
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