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An efficient sequential design of clinical trials

We propose an efficient group sequential monitoring rule for clinical trials. At each interim analysis both efficacy and futility are evaluated through a specified loss structure together with the predicted power. The proposed design is robust to a wide range of priors, and achieves the specified po...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Cheng, Yi, Shen, Yu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530214/
https://ncbi.nlm.nih.gov/pubmed/23275685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jspi.2012.07.015
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