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An analysis of adaptive design variations on the sequential parallel comparison design for clinical trials
BACKGROUND: Currently, a growing placebo response rate has been observed in clinical trials for antidepressant drugs, a phenomenon that has made it increasingly difficult to demonstrate efficacy. The sequential parallel comparison design (SPCD) is a clinical trial design that was proposed to address...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612388/ https://ncbi.nlm.nih.gov/pubmed/23283576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774512468806 |
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