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CD73 and adenosine generation in the creation of regulatory microenvironments
Extracellular adenosine 5′-triphosphate (ATP) acts on many immune cells to promote inflammation. Conversely, the ATP metabolite adenosine is mainly an anti-inflammatory molecule. The ecto-enzymes CD39 and CD73 can dephosphorylate extracellular ATP to adenosine, thereby controlling this important pat...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530089/ https://ncbi.nlm.nih.gov/pubmed/23199317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04623.x |
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