Interleukin-2/anti-interleukin-2 monoclonal antibody immune complex suppresses collagen-induced arthritis in mice by fortifying interleukin-2/STAT5 signalling pathways

In this study, we investigated the effects of administration of interleukin-2 (IL-2)/JES6-1 (anti-IL-2 monoclonal antibody) immune complexes on the expansion and activation of regulatory T (Treg) cells, the down-regulation of T helper type 17 (Th17) cells, and the control of the severity of collagen...

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Detalhes bibliográficos
Main Authors: Lee, Seon-Yeong, Cho, Mi-La, Oh, Hye-Jwa, Ryu, Jun-Geol, Park, Min-Jung, Jhun, Joo-Yeon, Park, Mi-Kyung, Stone, John C, Ju, Ji-Hyun, Hwang, Sue-Yun, Park, Sung-Hwan, Surh, Charles D, Kim, Ho-Youn
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530086/
https://ncbi.nlm.nih.gov/pubmed/23167249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12008
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