Interferon Gamma Suppresses Collagen-Induced Arthritis by Regulation of Th17 through the Induction of Indoleamine-2,3-Deoxygenase

C57BL/6 mice are known to be resistant to the development of collagen-induced arthritis (CIA). However, they show a severe arthritic phenotype when the Ifng gene is deleted. Although it has been proposed that IFN-γ suppresses inflammation in CIA via suppressing Th17 which is involved in the pathogen...

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Bibliografiska uppgifter
Huvudupphovsmän: Lee, Jaeseon, Lee, Jennifer, Park, Mi-Kyung, Lim, Mi-Ae, Park, Eun-Mi, Kim, Eun-kyung, Yang, Eun-Ji, Lee, Seon-Yeong, Jhun, Joo-Yeon, Park, Sung-Hwan, Kim, Ho-Youn, Cho, Mi-La
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628800/
https://ncbi.nlm.nih.gov/pubmed/23613752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060900
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