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Role of recombination activating genes in the generation of antigen receptor diversity and beyond

V(D)J recombination is the process by which antibody and T-cell receptor diversity is attained. During this process, antigen receptor gene segments are cleaved and rejoined by non-homologous DNA end joining for the generation of combinatorial diversity. The major players of the initial process of cl...

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Detalhes bibliográficos
Main Authors: Nishana, Mayilaadumveettil, Raghavan, Sathees C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530083/
https://ncbi.nlm.nih.gov/pubmed/23039142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12009
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