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A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

Chaperone-mediated autophagy (CMA) is a selective mechanism for the degradation of soluble proteins in lysosomes. CMA contributes to cellular quality control and is activated as part of the cellular response to different stressors. Defective CMA has been identified in aging and different age-related...

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Bibliographic Details
Main Authors: Koga, Hiroshi, Martinez-Vicente, Marta, Macian, Fernando, Verkhusha, Vladislav V, Cuervo, Ana Maria
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529934/
https://ncbi.nlm.nih.gov/pubmed/21750540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1393
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