Phosphonopeptide antibacterial agents related to alafosfalin: design, synthesis, and structure-activity relationships.

Dipeptide variants of alafosfalin (L-alanyl-L-1-aminoethylphosphonic acid) with substantial differences in potency and antibacterial spectrum in vitro and in vivo have been synthesized. Certain dipeptides with alternatives to the L-alanyl residue had broader antibacterial spectra; activity against P...

Description complète

Détails bibliographiques

Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Atherton, F R, Hall, M J, Hassall, C H, Holmes, S W, Lambert, R W, Lloyd, W J, Ringrose, P S
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1980
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352986/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7016027/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.6.897
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!