Phosphonopeptide antibacterial agents related to alafosfalin: design, synthesis, and structure-activity relationships.

Dipeptide variants of alafosfalin (L-alanyl-L-1-aminoethylphosphonic acid) with substantial differences in potency and antibacterial spectrum in vitro and in vivo have been synthesized. Certain dipeptides with alternatives to the L-alanyl residue had broader antibacterial spectra; activity against P...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Atherton, F R, Hall, M J, Hassall, C H, Holmes, S W, Lambert, R W, Lloyd, W J, Ringrose, P S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 1980
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352986/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7016027/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.6.897
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