Risks of Primary Extracolonic Cancers Following Colorectal Cancer in Lynch Syndrome

BACKGROUND: Lynch syndrome is a highly penetrant cancer predisposition syndrome caused by germline mutations in DNA mismatch repair (MMR) genes. We estimated the risks of primary cancers other than colorectal cancer following a diagnosis of colorectal cancer in mutation carriers. METHODS: We obtaine...

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Main Authors: Win, Aung Ko, Lindor, Noralane M., Young, Joanne P., Macrae, Finlay A., Young, Graeme P., Williamson, Elizabeth, Parry, Susan, Goldblatt, Jack, Lipton, Lara, Winship, Ingrid, Leggett, Barbara, Tucker, Katherine M., Giles, Graham G., Buchanan, Daniel D., Clendenning, Mark, Rosty, Christophe, Arnold, Julie, Levine, A. Joan, Haile, Robert W., Gallinger, Steven, Marchand, Loïc Le, Newcomb, Polly A., Hopper, John L., Jenkins, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529597/
https://ncbi.nlm.nih.gov/pubmed/22933731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs351
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