Mitochondria Superoxide Anion Production Contributes to Geranylgeraniol-Induced Death in Leishmania amazonensis

Here we demonstrate the activity of geranylgeraniol, the major bioactive constituent from seeds of Bixa orellana, against Leishmania amazonensis. Geranylgeraniol was identified through (1)H and (13)C nuclear magnetic resonance imaging and DEPT. The compound inhibited the promastigote and intracellul...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lopes, Milene Valéria, Desoti, Vânia Cristina, Caleare, Angelo de Oliveira, Ueda-Nakamura, Tânia, Silva, Sueli Oliveira, Nakamura, Celso Vataru
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529489/
https://ncbi.nlm.nih.gov/pubmed/23304195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/298320
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars