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The In Vivo Role of Nuclear Receptor Corepressors in Thyroid Hormone Action

BACKGROUND: The thyroid hormone receptor (TR) isoforms interact with a variety of coregulators depending upon the availability of T(3) to mediate their transcriptional effect. Classically, in the absence of ligand, the TRs recruit the nuclear corepressors, NCoR and SMRT, to mediate transcriptional r...

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Autors principals: Astapova, Inna, Hollenberg, Anthony N.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529203/
https://ncbi.nlm.nih.gov/pubmed/22801336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2012.07.001
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