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Efficient (18)F-Labeling of Large 37-Amino Acid pHLIP Peptide Analogues and their Biological Evaluation

Solid tumors often develop an acidic microenvironment, which plays a critical role in tumor progression and is associated with increased level of invasion and metastasis. The 37-residue pH (low) insertion peptide (pHLIP(®)) is under study as an imaging platform because of its unique ability to inser...

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Detalhes bibliográficos
Main Authors: Daumar, Pierre, Wanger-Baumann, Cindy A., Pillarsetty, NagaVaraKishore, Fabrizio, Laura, Carlin, Sean D., Andreev, Oleg A., Reshetnyak, Yana K., Lewis, Jason S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529145/
https://ncbi.nlm.nih.gov/pubmed/22784215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc3000222
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