Identification of Oct4-activating compounds that enhance reprogramming efficiency

One of the hurdles for practical application of induced pluripotent stem cells (iPSC) is the low efficiency and slow process of reprogramming. Octamer-binding transcription factor 4 (Oct4) has been shown to be an essential regulator of embryonic stem cell (ESC) pluripotency and key to the reprogramm...

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Bibliographic Details
Main Authors: Li, Wendong, Tian, E, Chen, Zhao-Xia, Sun, GuoQiang, Ye, Peng, Yang, Su, Lu, Dave, Xie, Jun, Ho, Thach-Vu, Tsark, Walter M., Wang, Charles, Horne, David A., Riggs, Arthur D., Yip, M. L. Richard, Shi, Yanhong
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529047/
https://ncbi.nlm.nih.gov/pubmed/23213213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219181110
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