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Survivin Improves Reprogramming Efficiency of Human Neural Progenitors by Single Molecule OCT4

Induced pluripotent stem (iPS) cells have been generated from human somatic cells by ectopic expression of four Yamanaka factors. Here, we report that Survivin, an apoptosis inhibitor, can enhance iPS cells generation from human neural progenitor cells (NPCs) together with one factor OCT4 (1F-OCT4-S...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Zhou, Shixin, Liu, Yinan, Feng, Ruopeng, Wang, Caiyun, Jiang, Sibo, Zhang, Xiaoyan, Lan, Feng, Li, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5128714/
https://ncbi.nlm.nih.gov/pubmed/27974895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4729535
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