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Efficient Feeder-Free Episomal Reprogramming with Small Molecules

Genetic reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) could offer replenishable cell sources for transplantation therapies. To fulfill their promises, human iPSCs will ideally be free of exogenous DNA (footprint-free), and be derived and cultured in chemically define...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yu, Junying, Chau, Kevin Fongching, Vodyanik, Maxim A., Jiang, Jinlan, Jiang, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046978/
https://ncbi.nlm.nih.gov/pubmed/21390254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017557
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