Neurocardiac dysregulation and neurogenic arrhythmias in a transgenic mouse model of Huntington's disease

Huntington's disease (HD) is a heritable neurodegenerative disorder, with heart disease implicated as one major cause of death. While the responsible mechanism remains unknown, autonomic nervous system (ANS) dysfunction may play a role. We studied the cardiac phenotype in R6/1 transgenic mice a...

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Bibliografiske detaljer
Main Authors: Kiriazis, Helen, Jennings, Nicole L, Davern, Pamela, Lambert, Gavin, Su, Yidan, Pang, Terence, Du, Xin, La Greca, Luisa, Head, Geoffrey A, Hannan, Anthony J, Du, Xiao-Jun
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2012
Fag:
Neuroscience: Neurobiology of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528995/
https://ncbi.nlm.nih.gov/pubmed/22890713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.238113
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