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A Tale of Two Maladies? Pathogenesis of Depression with and without the Huntington’s Disease Gene Mutation
Huntington’s disease (HD) is an autosomal dominant disorder caused by a tandem repeat expansion encoding an expanded tract of glutamines in the huntingtin protein. HD is progressive and manifests as psychiatric symptoms (including depression), cognitive deficits (culminating in dementia), and motor...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3705171/ https://ncbi.nlm.nih.gov/pubmed/23847583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2013.00081 |
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