TARP-associated AMPA receptors display an increased maximum channel conductance and multiple kinetically distinct open states

Fast excitatory synaptic transmission in the CNS is mediated mainly by AMPA-type glutamate receptors (AMPARs), whose biophysical properties are dramatically modulated by the presence of transmembrane AMPAR regulatory proteins (TARPs). To help construct a kinetic model that will realistically describ...

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Hlavní autoři: Shelley, Chris, Farrant, Mark, Cull-Candy, Stuart G
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2012
Témata:
Neuroscience: Cellular/Molecular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528987/
https://ncbi.nlm.nih.gov/pubmed/22988139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.238006
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