Comparative nephrotoxicity of SCH 21420 and amikacin in rats.

The nephrotoxic potentials of the new aminoglycoside SCH 21420 and amikacin were compared in a rat model. Groups of rats received 100, 200, 300, or 600 mg of either drug per kg per day for 14 days. Enzymuria, urine osmolality, protein excretion, and blood urea nitrogen were monitored at periodic int...

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出版年:	Antimicrob Agents Chemother
主要な著者:	Rankin, L I, Luft, F C, Yum, M N, Sloan, R S, Dinwiddie, C B, Isaacs, L L
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1979
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/518078/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.4.491
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