Comparative nephrotoxicity of SCH 21420 and amikacin in rats.

The nephrotoxic potentials of the new aminoglycoside SCH 21420 and amikacin were compared in a rat model. Groups of rats received 100, 200, 300, or 600 mg of either drug per kg per day for 14 days. Enzymuria, urine osmolality, protein excretion, and blood urea nitrogen were monitored at periodic int...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Rankin, L I, Luft, F C, Yum, M N, Sloan, R S, Dinwiddie, C B, Isaacs, L L
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 1979
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/518078/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.4.491
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