Comparative nephrotoxicity of SCH 21420 and amikacin in rats.

The nephrotoxic potentials of the new aminoglycoside SCH 21420 and amikacin were compared in a rat model. Groups of rats received 100, 200, 300, or 600 mg of either drug per kg per day for 14 days. Enzymuria, urine osmolality, protein excretion, and blood urea nitrogen were monitored at periodic int...

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Εκδόθηκε σε:	Antimicrob Agents Chemother
Κύριοι συγγραφείς:	Rankin, L I, Luft, F C, Yum, M N, Sloan, R S, Dinwiddie, C B, Isaacs, L L
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 1979
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/518078/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.4.491
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