Comparative nephrotoxicity of SCH 21420 and amikacin in rats.

The nephrotoxic potentials of the new aminoglycoside SCH 21420 and amikacin were compared in a rat model. Groups of rats received 100, 200, 300, or 600 mg of either drug per kg per day for 14 days. Enzymuria, urine osmolality, protein excretion, and blood urea nitrogen were monitored at periodic int...

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Библиографические подробности

Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	Rankin, L I, Luft, F C, Yum, M N, Sloan, R S, Dinwiddie, C B, Isaacs, L L
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1979
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/518078/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.4.491
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