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Rapidly Relocating Molecules Between Organelles to Manipulate Small GTPase Activity

Chemically-inducible rapid manipulation of small GTPase activity has proven a powerful approach to dissect complex spatio-temporal signaling of these molecular switches. However, overexpression of these synthetic molecular probes freely in the cytosol often results in elevated background activity be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Phua, Siew Cheng, Pohlmeyer, Christopher, Inoue, Takanari
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528809/
https://ncbi.nlm.nih.gov/pubmed/22999378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300280k
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