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Post-translational protein modification by O-linked N-acetyl-glucosamine: Its role in mediating the adverse effects of diabetes on the heart

The post-translation attachment of O-linked N-acetylglucosamine, or O-GlcNAc, to serine and threonine residues of nuclear and cytoplasmic proteins is increasingly recognized as a key regulator of diverse cellular processes. O-GlcNAc synthesis is essential for cell survival and it has been shown that...

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Hlavní autoři: McLarty, Jennifer L., Marsh, Susan A., Chatham, John C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528804/
https://ncbi.nlm.nih.gov/pubmed/22985933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.08.006
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