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Glucosamine cardioprotection in perfused rat heart associated with increased O-Linked N-acetylglucosamine protein modification and altered p38 activation

We have shown that in the perfused heart glucosamine improved functional recovery following ischemia and this appeared to be mediated via an increase in O-Linked N-acetylglucosamine (O-GlcNAc) levels on nucleocytoplasmic proteins. Several kinase pathways, specifically Akt and the mitogen activated p...

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Main Authors: Fülöp, Norbert, Zhang, Zhenghao, Marchase, Richard B., Chatham, John C.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850194/
https://ncbi.nlm.nih.gov/pubmed/17208994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01091.2006
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