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Synthesis of Vertex-Differentiated Icosahedral closo-Boranes: Polyfunctional Scaffolds for Targeted Drug Delivery

[Image: see text] We report methods for the synthesis of vertex-differentiated icosahedral closo-boranes. A single B-OH vertex of the icosahedral borane [closo-B(12)(OH)(12)](2−) was derivatized to prepare [closo-B(12)(OR)(OH)(11)](2−) using optimized alkylation conditions and purification procedure...

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Autors principals: Goswami, Lalit N., Houston, Zachary H., Sarma, Saurav J., Li, Hairong, Jalisatgi, Satish S., Hawthorne, M. Frederick
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528802/
https://ncbi.nlm.nih.gov/pubmed/23164043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo3021314
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