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Telomerase Immortalization of Human Corneal Endothelial Cells Yields Functional Hexagonal Monolayers

Human corneal endothelial cells (HCEnCs) form a monolayer of hexagonal cells whose main function is to maintain corneal clarity by regulating corneal hydration. HCEnCs are derived from neural crest and are arrested in the post-mitotic state. Thus cell loss due to aging or corneal endothelial disorde...

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Autori principali: Schmedt, Thore, Chen, Yuming, Nguyen, Tracy T., Li, Shimin, Bonanno, Joseph A., Jurkunas, Ula V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528758/
https://ncbi.nlm.nih.gov/pubmed/23284695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051427
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