Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia

There is no effective treatment for the cardiomyopathy of the most common autosomal recessive ataxia, Friedreich ataxia (FA). This disease is due to decreased expression of the mitochondrial protein, frataxin, which leads to alterations in mitochondrial iron (Fe) metabolism. The identification of po...

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Autors principals: Whitnall, Megan, Rahmanto, Yohan Suryo, Huang, Michael L.-H., Saletta, Federica, Lok, Hiu Chuen, Gutiérrez, Lucía, Lázaro, Francisco J., Fleming, Adam J., St. Pierre, Tim G., Mikhael, Marc R., Ponka, Prem, Richardson, Des R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528580/
https://ncbi.nlm.nih.gov/pubmed/23169664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215349109
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