Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub

Antigen receptor locus V(D)J recombination requires interactions between widely separated variable (V), diversity (D), and joining (J) gene segments, but the mechanisms that generate these interactions are not well understood. Here we assessed mechanisms that direct developmental stage-specific long...

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Autori principali: Shih, Han-Yu, Verma-Gaur, Jiyoti, Torkamani, Ali, Feeney, Ann J., Galjart, Niels, Krangel, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528579/
https://ncbi.nlm.nih.gov/pubmed/23169622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214131109
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