Endogenously produced nitric oxide mitigates sensitivity of melanoma cells to cisplatin

Melanoma patients experience inferior survival after biochemotherapy when their tumors contain numerous cells expressing the inducible isoform of NO synthase (iNOS) and elevated levels of nitrotyrosine, a product derived from NO. Although several lines of evidence suggest that NO promotes tumor grow...

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Bibliographic Details
Main Authors: Godoy, Luiz C., Anderson, Chase T. M., Chowdhury, Rajdeep, Trudel, Laura J., Wogan, Gerald N.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528548/
https://ncbi.nlm.nih.gov/pubmed/23185001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218938109
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