Phase I Study and Biomarker Analysis of Lapatinib and Concurrent Radiation for Locally Advanced Breast Cancer

PURPOSE. This phase I study assessed the toxicity and safety of combining daily lapatinib with radiation therapy. Sequential tumor biopsies were obtained to evaluate changes in biomarkers, such as epidermal growth factor receptor (EGFR) and human EGFR-2 (HER2) signaling pathways. METHODS. Eligibilit...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Kimple, Randall J., Horton, Janet K., Livasy, Chad A., Shields, Janiel M., Lawrence, Julia A., Chiu, WingKeung M., Ivanova, Anastasia, Ollila, David W., Carey, Lisa A., Halle, Jan S., Sartor, Carolyn I., Dees, E. Claire
Formato: Artigo
Idioma:Inglês
Publicado: AlphaMed Press 2012
Assuntos:
Breast Cancer
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528381/
https://ncbi.nlm.nih.gov/pubmed/23006498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2012-0256
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares