Toll-like receptor 2 ligands promote microglial cell death by inducing autophagy

Microglial cells are phagocytes in the central nervous system (CNS) and become activated in pathological conditions, resulting in microgliosis, manifested by increased cell numbers and inflammation in the affected regions. Thus, controlling microgliosis is important to prevent pathological damage to...

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Main Authors: Arroyo, Daniela S., Soria, Javier A., Gaviglio, Emilia A., Garcia-Keller, Constanza, Cancela, Liliana M., Rodriguez-Galan, Maria C., Wang, Ji Ming, Iribarren, Pablo
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2013
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528320/
https://ncbi.nlm.nih.gov/pubmed/23073832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-214312
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