Phosphatidyl-Inositol-3 Kinase Inhibitors Regulate Peptidoglycan-Induced Myeloid Leukocyte Recruitment, Inflammation, and Neurotoxicity in Mouse Brain

Acute brain injury leads to the recruitment and activation of immune cells including resident microglia and infiltrating peripheral myeloid cells (MC), which contribute to the inflammatory response involved in neuronal damage. We previously reported that TLR2 stimulation by peptidoglycan (PGN) from...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Arroyo, Daniela S., Gaviglio, Emilia A., Peralta Ramos, Javier M., Bussi, Claudio, Avalos, Maria P., Cancela, Liliana M., Iribarren, Pablo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914281/
https://ncbi.nlm.nih.gov/pubmed/29719536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00770
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