Phosphatidyl-Inositol-3 Kinase Inhibitors Regulate Peptidoglycan-Induced Myeloid Leukocyte Recruitment, Inflammation, and Neurotoxicity in Mouse Brain

Acute brain injury leads to the recruitment and activation of immune cells including resident microglia and infiltrating peripheral myeloid cells (MC), which contribute to the inflammatory response involved in neuronal damage. We previously reported that TLR2 stimulation by peptidoglycan (PGN) from...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Arroyo, Daniela S., Gaviglio, Emilia A., Peralta Ramos, Javier M., Bussi, Claudio, Avalos, Maria P., Cancela, Liliana M., Iribarren, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914281/
https://ncbi.nlm.nih.gov/pubmed/29719536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00770
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