Phosphatidyl-Inositol-3 Kinase Inhibitors Regulate Peptidoglycan-Induced Myeloid Leukocyte Recruitment, Inflammation, and Neurotoxicity in Mouse Brain

Acute brain injury leads to the recruitment and activation of immune cells including resident microglia and infiltrating peripheral myeloid cells (MC), which contribute to the inflammatory response involved in neuronal damage. We previously reported that TLR2 stimulation by peptidoglycan (PGN) from...

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Vydáno v:Front Immunol
Hlavní autoři: Arroyo, Daniela S., Gaviglio, Emilia A., Peralta Ramos, Javier M., Bussi, Claudio, Avalos, Maria P., Cancela, Liliana M., Iribarren, Pablo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914281/
https://ncbi.nlm.nih.gov/pubmed/29719536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00770
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