Phosphatidyl-Inositol-3 Kinase Inhibitors Regulate Peptidoglycan-Induced Myeloid Leukocyte Recruitment, Inflammation, and Neurotoxicity in Mouse Brain

Acute brain injury leads to the recruitment and activation of immune cells including resident microglia and infiltrating peripheral myeloid cells (MC), which contribute to the inflammatory response involved in neuronal damage. We previously reported that TLR2 stimulation by peptidoglycan (PGN) from...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Arroyo, Daniela S., Gaviglio, Emilia A., Peralta Ramos, Javier M., Bussi, Claudio, Avalos, Maria P., Cancela, Liliana M., Iribarren, Pablo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914281/
https://ncbi.nlm.nih.gov/pubmed/29719536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00770
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