Toll-like receptor 2 ligands promote microglial cell death by inducing autophagy

Microglial cells are phagocytes in the central nervous system (CNS) and become activated in pathological conditions, resulting in microgliosis, manifested by increased cell numbers and inflammation in the affected regions. Thus, controlling microgliosis is important to prevent pathological damage to...

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Autores principales: Arroyo, Daniela S., Soria, Javier A., Gaviglio, Emilia A., Garcia-Keller, Constanza, Cancela, Liliana M., Rodriguez-Galan, Maria C., Wang, Ji Ming, Iribarren, Pablo
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2013
Materias:
Research Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528320/
https://ncbi.nlm.nih.gov/pubmed/23073832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-214312
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