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Tim-1 Regulates Th2 Responses in an Airway Hypersensitivity Model

T cell immunoglobulin mucin-1 (Tim-1) is a transmembrane protein postulated to be a key regulator of Th2-type immune responses. This hypothesis is based in part upon genetic studies associating Tim-1 polymorphisms in mice with a bias toward airway hyperresponsiveness and the development of Th2-type...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Curtiss, Miranda, Gorman, Jacob V., Businga, Thomas R., Traver, Geri, Singh, Melody, Meyerholz, David K., Kline, Joel N., Colgan, John D., Rothman, Paul B., Cassel, Suzanne L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528103/
https://ncbi.nlm.nih.gov/pubmed/22144095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141581
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