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Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity

Protein sulfenylation is a post-translational modification of emerging importance in higher eukaryotes. However, investigation of its diverse roles remains challenging, particularly within a native cellular environment. Herein we report the development and application of DYn-2, a new chemoselective...

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Detalhes bibliográficos
Main Authors: Paulsen, Candice E, Truong, Thu H, Garcia, Francisco J, Homann, Arne, Gupta, Vinayak, Leonard, Stephen E, Carroll, Kate S
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528018/
https://ncbi.nlm.nih.gov/pubmed/22158416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.736
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