Foamy Virus Envelope Protein Is a Substrate for Signal Peptide Peptidase-like 3 (SPPL3)

Signal peptide peptidase (SPP), its homologs, the SPP-like proteases SPPL2a/b/c and SPPL3, as well as presenilin, the catalytic subunit of the γ-secretase complex, are intramembrane-cleaving aspartyl proteases of the GxGD type. In this study, we identified the 18-kDa leader peptide (LP18) of the foa...

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Bibliographische Detailangaben
Hauptverfasser: Voss, Matthias, Fukumori, Akio, Kuhn, Peer-Hendrik, Künzel, Ulrike, Klier, Bärbel, Grammer, Gudula, Haug-Kröper, Martina, Kremmer, Elisabeth, Lichtenthaler, Stefan F., Steiner, Harald, Schröder, Bernd, Haass, Christian, Fluhrer, Regina
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527927/
https://ncbi.nlm.nih.gov/pubmed/23132852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.371369
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