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TMPRSS2-ERG Fusion Gene Expression in Prostate Tumor Cells and Its Clinical and Biological Significance in Prostate Cancer Progression

TMPRSS2-Ets gene fusions were identified in prostate cancers where the promoter of transmembrane protease, serine 2 (TMPRSS2) fused with coding sequence of the erythroblastosis virus E26 (Ets) gene family members. TMPRSS2 is an androgen responsive transmembrane serine protease. Ets family members ar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: St. John, Jason, Powell, Katelyn, Conley-LaComb, M. Katie, Chinni, Sreenivasa R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527835/
https://ncbi.nlm.nih.gov/pubmed/23264855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/1948-5956.1000119
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