ERG/AKR1C3/AR constitutes a feed-forward loop for AR signaling in prostate cancer cells

PURPOSE: Intratumoral androgen synthesis in prostate cancer (PCa) contributes to the development of castration-resistant prostate cancer (CRPC). Several enzymes responsible for androgen biosynthesis have been shown to be overexpressed in CRPC, thus contributing to CRPC in a castrated environment. Th...

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Publicado en:Clin Cancer Res
Main Authors: Powell, Katelyn, Semaan, Louie, Conley-LaComb, M. Katie, Asangani, Irfan, Wu, Yi-Mi, Ginsburg, Kevin B., Williams, Julia, Squire, Jeremy A., Maddipati, Krishna R., Cher, Michael L., Chinni, Sreenivasa R.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976600/
https://ncbi.nlm.nih.gov/pubmed/25754347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2352
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