Early ischaemic preconditioning requires Akt- and PKA-mediated activation of eNOS via serine1176 phosphorylation

AIMS: The role of endothelial nitric oxide synthase (eNOS)/NO signalling is well documented in late ischaemic preconditioning (IPC); however, the role of eNOS and its activation in early IPC remains controversial. This study investigates the role of eNOS in early IPC and the signalling pathways and...

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Bibliographic Details
Main Authors: Yang, Changjun, Talukder, M.A. Hassan, Varadharaj, Saradhadevi, Velayutham, Murugesan, Zweier, Jay L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527763/
https://ncbi.nlm.nih.gov/pubmed/22977010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs287
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