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The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability

BACKGROUND: Bloom syndrome is a rare cancer-prone disorder in which the cells of affected persons have a high frequency of somatic mutation and genomic instability. Bloom syndrome cells have a distinctive high frequency of sister chromatid exchange and quadriradial formation. BLM, the protein altere...

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Udgivet i:BMC Cell Biol
Principais autores: Yankiwski, Victor, Noonan, James P, Neff, Norma F
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2001
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC35277/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11472631/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-2-11
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