The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability
BACKGROUND: Bloom syndrome is a rare cancer-prone disorder in which the cells of affected persons have a high frequency of somatic mutation and genomic instability. Bloom syndrome cells have a distinctive high frequency of sister chromatid exchange and quadriradial formation. BLM, the protein altere...
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| Veröffentlicht in: | BMC Cell Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2001
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC35277/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11472631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-2-11 |
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